Board of Directors

  • Stanley T. Crooke, M.D., Ph.D.
    Stanley T. Crooke, M.D., Ph.D.
    Chairman of the Board and Chief Executive Officer, Ionis Pharmaceuticals, Inc.

    Dr. Crooke is founder, chairman, and chief executive officer of Ionis Pharmaceuticals. During his tenure at Ionis, he has led the scientific development of a new platform for drug discovery, antisense technology and engineered the creation of one of the largest and more advanced deve

    Chairman of the Board and Chief Executive Officer, Ionis Pharmaceuticals, Inc.
  • Spencer R. Berthelsen, M.D.
    Spencer R. Berthelsen, M.D.
    Chairman and Managing Director, Kelsey-Seybold Clinic

    Dr. Berthelsen has served as a Director of Ionis since May 2002. Since 1980, he has practiced Internal Medicine with the Kelsey Seybold Clinic, a 400 physician medical group based in the Texas Medical Center in Houston. Dr. Berthelsen has served in various senior leadership positions at

    Chairman and Managing Director, Kelsey-Seybold Clinic
  • Breaux Castleman
    Breaux Castleman
    President and Chief Executive Officer, Syntiro Healthcare Services, Inc.

    Mr. Castleman has served as a Director of Ionis since June 2013. Since August 2001, Mr. Castleman has been president and chief executive officer of Syntiro Healthcare Services, Inc., a healthcare investment company, which sold its operations as a service provider of integrated care mana

    President and Chief Executive Officer, Syntiro Healthcare Services, Inc.
  • Joseph Klein, III
    Joseph Klein, III
    Managing Director, Gauss Capital Advisors, LLC

    Mr. Klein has served as a Director of Ionis since December 2005. Mr. Klein is currently Managing Director of Gauss Capital Advisors, LLC, a financial consulting and investment advisory firm focused on biopharmaceuticals, which he founded in March 1998. From September 2003 to December 20

    Managing Director, Gauss Capital Advisors, LLC
  • Joseph Loscalzo, M.D., Ph.D.
    Joseph Loscalzo, M.D., Ph.D.
    Head of Department of Medicine and Physician-in-Chief, Brigham & Woman's Hospital, Harvard Medical School

    Dr. Loscalzo is Hersey Professor of the Theory and Practice of Medicine at Harvard Medical School, Chairman of the Department of Medicine, and Physician-in-Chief at Brigham and Women’s Hospital. Dr. Loscalzo received his A.B. degree, summa cum laude, his Ph.D. in biochemistry, and his M

    Head of Department of Medicine and Physician-in-Chief, Brigham & Woman's Hospital, Harvard Medical School
  • Frederick T. Muto, Esq.*
    Frederick T. Muto, Esq.*
    Partner, Cooley LLP

    Mr. Muto has served as a Director of Ionis since March 2001. Mr. Muto joined the law firm of Cooley LLP, outside counsel to Ionis, in 1980 and became a partner in 1986. He is a founding partner of Cooley LLP’s San Diego office and was Chair of the firm’s Business Department.

    Partner, Cooley LLP
  • B. Lynne Parshall, Esq.
    B. Lynne Parshall, Esq.
    Director and Chief Operating Officer, Ionis Pharmaceuticals, Inc.

    Ms. Parshall is Director and Chief Operating Officer of Ionis Pharmaceuticals. She is responsible for overseeing the operations of finance, legal, patents, manufacturing, information technology, regulatory and alliance management, health and safety, facilities, corporate communications,

    Director and Chief Operating Officer, Ionis Pharmaceuticals, Inc.
  • Joseph H. Wender
    Joseph H. Wender
    Senior Consultant, Goldman Sachs & Co.

    Mr. Wender has served as a Director of Ionis since January 1994. Mr. Wender began with Goldman, Sachs & Co. in 1971 and became a General Partner of that firm in 1982, where he headed the Financial Institutions Group for over a decade. Since January 2008, he has been a Senior Consu

    Senior Consultant, Goldman Sachs & Co.

* Mr. Frederick T. Muto, Esq. serves as counsel to the Compensation Committee and Nominating, Governance and Review Committee.