Investors & Media


Brett P. Monia, Ph.D.

Chief Operating Officer and Senior Vice President
Translational Medicine

Dr. Monia is a founding member of Ionis and is the Chief Operating Officer and Senior Vice President of Translational Medicine. In March 2019, he was appointed to the Ionis board of directors. His contributions include research into the medicinal chemistry and mechanisms of action of oligonucleotide-based drugs in cell culture and in animals, and in the establishment of numerous preclinical and clinical programs, many of which have resulted in clinical proof of concept in various therapeutic areas, including oncology, metabolic disease, inflammation, cardiovascular disease, and rare diseases.

Dr. Monia’s publication record exceeds 150 primary research manuscripts, reviews and book chapters, and he is an inventor on more than 100 issued patents. In addition, he serves as a Senior Editor for the journal Nucleic Acid Therapeutics and also serves on the editorial boards for a number of additional scientific journals, is a member of the American Association of Cancer Research, the American Diabetes Association, the American Association for the Study of Liver Diseases, the American Society of Hematology, and serves on the Board of Directors for the Oligonucleotide Therapeutics Society. Dr. Monia also serves on the Board of Directors for Dynacure Therapeutics and is an adjunct professor of biology at San Diego State University where he lectures at the graduate level on pharmacology.
Dr. Monia received his Ph.D. in Pharmacology at the University of Pennsylvania and B.S. degrees in Molecular Biology and Analytical Chemistry at Stockton State College, in Pomona, New Jersey.