Investors & Media

Ownership Profile

Ownership Profile

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Fidelity Management & Research Company LLC 21,320,886 15.04 139,384 3/31/22
T. Rowe Price Associates, Inc. 14,350,460 10.12 1,860,180 3/31/22
The Vanguard Group, Inc. 12,099,034 8.53 91,958 3/31/22
Bellevue Asset Management AG 9,918,073 6.99 -437,050 3/31/22
BlackRock Institutional Trust Company, N.A. 7,046,653 4.97 -66,434 3/31/22
ClearBridge Investments, LLC 6,476,033 4.57 593,051 3/31/22
ARK Investment Management LLC 6,171,308 4.35 -911,948 3/31/22
State Street Global Advisors (US) 4,030,646 2.84 124,271 3/31/22
Camber Capital Management LP 3,000,000 2.12 1,610,000 3/31/22
Tweedy, Browne Company LLC 2,925,102 2.06 2,925,102 3/31/22

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
BB Biotech Fd 9,732,973 6.86 620,000 3/31/22
Fidelity Growth Company Fund 7,547,069 5.32 -44,927 3/31/22
ARK Genomic Revolution ETF 5,927,986 4.18 -274,910 4/30/22
T. Rowe Price Mid-Cap Growth Fund 4,248,800 3.00 547,400 3/31/22
Vanguard Total Stock Market Index Fund 3,484,507 2.46 50,394 4/30/22
Vanguard Small-Cap Index Fund 3,011,390 2.12 3,056 4/30/22
ClearBridge Aggressive Growth Fund 2,086,537 1.47 -- 3/31/22
SPDR S&P Biotech ETF 1,864,790 1.32 11,400 4/30/22
Fidelity Growth Company K6 Fund 1,852,022 1.31 55,335 3/31/22
Vanguard Extended Market Index Fund 1,851,860 1.31 7,368 4/30/22

* Insider values reflect direct beneficial ownership.

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