Investors & Media

Ownership Profile

Ownership Profile

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Fidelity Management & Research Company LLC 21,093,896 14.96 168,862 3/31/21
The Vanguard Group, Inc. 12,604,149 8.94 359,761 3/31/21
T. Rowe Price Associates, Inc. 12,580,056 8.92 -534,911 3/31/21
Bellevue Asset Management AG 8,984,234 6.37 -65,858 3/31/21
BlackRock Institutional Trust Company, N.A. 7,877,954 5.59 -23,785 3/31/21
ClearBridge Investments, LLC 7,402,967 5.25 487,820 3/31/21
Biogen Inc 5,750,577 4.08 -5,750,576 12/31/19
ARK Investment Management LLC 5,142,271 3.65 2,742,717 3/31/21
State Street Global Advisors (US) 3,409,571 2.42 -503,757 3/31/21
Invesco Advisers, Inc. 2,303,171 1.63 -924,974 3/31/21

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
BB Biotech Fd 8,166,962 5.79 -32,951 3/31/21
ARK Genomic Revolution ETF 7,859,210 5.58 1,890,358 5/31/21
Fidelity Growth Company Fund 7,745,607 5.49 -108,807 4/30/21
Vanguard Total Stock Market Index Fund 3,827,997 2.72 49,928 5/31/21
T. Rowe Price Mid-Cap Growth Fund 3,750,000 2.66 -- 3/31/21
Vanguard Small-Cap Index Fund 3,303,625 2.34 18,710 5/31/21
ClearBridge Aggressive Growth Fund 2,306,791 1.64 -- 12/31/20
Vanguard Small-Cap Growth Index Fund 2,155,607 1.53 7,729 5/31/21
Vanguard Extended Market Index Fund 2,020,562 1.43 12,819 5/31/21
Fidelity Select Biotechnology Portfolio 1,722,677 1.22 -- 4/30/21

* Insider values reflect direct beneficial ownership.

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