Investors & Media

Ownership Profile

Ownership Profile

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Fidelity Management & Research Company LLC 21,320,886 15.04 139,384 3/31/22
T. Rowe Price Associates, Inc. 14,350,460 10.12 1,860,180 3/31/22
The Vanguard Group, Inc. 12,099,034 8.53 91,958 3/31/22
Bellevue Asset Management AG 9,918,073 6.99 -437,050 3/31/22
T. Rowe Price Investment Management, Inc. 7,819,762 5.51 118,658 6/30/22
BlackRock Institutional Trust Company, N.A. 7,046,653 4.97 -66,434 3/31/22
ClearBridge Investments, LLC 6,476,033 4.57 593,051 3/31/22
ARK Investment Management LLC 4,701,297 3.32 -1,470,011 6/30/22
State Street Global Advisors (US) 4,030,646 2.84 124,271 3/31/22
Camber Capital Management LP 3,000,000 2.12 1,610,000 3/31/22

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
BB Biotech Fd 9,732,973 6.86 620,000 3/31/22
Fidelity Growth Company Fund 7,304,746 5.15 -48,419 6/30/22
T. Rowe Price Mid-Cap Growth Fund 4,242,300 2.99 -6,500 6/30/22
ARK Genomic Revolution ETF 4,191,790 2.96 -317,077 6/30/22
Vanguard Total Stock Market Index Fund 3,544,794 2.50 24,578 6/30/22
Vanguard Small-Cap Index Fund 3,044,141 2.15 25,869 6/30/22
SPDR S&P Biotech ETF 2,090,794 1.47 16,182 7/31/22
ClearBridge Aggressive Growth Fund 2,086,537 1.47 -- 6/30/22
Fidelity Series Growth Company Fund 1,970,769 1.39 60,000 6/30/22
Vanguard Extended Market Index Fund 1,902,852 1.34 23,191 6/30/22

* Insider values reflect direct beneficial ownership.

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