Investors & Media

Ownership Profile

Ownership Profile

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Fidelity Management & Research Company LLC 21,269,560 14.98 -51,326 6/30/22
The Vanguard Group, Inc. 12,200,276 8.60 101,242 6/30/22
Bellevue Asset Management AG 9,776,528 6.89 -141,545 6/30/22
T. Rowe Price Investment Management, Inc. 7,834,062 5.52 -19,000 8/31/22
BlackRock Institutional Trust Company, N.A. 7,005,008 4.94 -41,645 6/30/22
ClearBridge Investments, LLC 6,005,818 4.23 -470,215 6/30/22
T. Rowe Price Associates, Inc. 4,808,770 3.39 -10,247,276 7/31/22
ARK Investment Management LLC 4,701,297 3.31 -1,470,011 6/30/22
State Street Global Advisors (US) 4,202,874 2.96 172,228 6/30/22
Tweedy, Browne Company LLC 2,726,778 1.92 -198,324 6/30/22

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
BB Biotech Fd 9,732,973 6.86 620,000 3/31/22
Fidelity Growth Company Fund 7,103,327 5.00 -9,516 8/31/22
T. Rowe Price Mid-Cap Growth Fund 4,242,300 2.99 -6,500 6/30/22
ARK Genomic Revolution ETF 3,786,485 2.67 -73,814 8/31/22
Vanguard Total Stock Market Index Fund 3,584,160 2.53 8,714 8/31/22
Vanguard Small-Cap Index Fund 3,056,218 2.15 4,130 8/31/22
ClearBridge Aggressive Growth Fund 2,086,537 1.47 -- 6/30/22
Fidelity Series Growth Company Fund 2,070,504 1.46 21,535 8/31/22
Vanguard Extended Market Index Fund 1,930,618 1.36 10,050 8/31/22
Fidelity Growth Company K6 Fund 1,902,344 1.34 -5,196 8/31/22

* Insider values reflect direct beneficial ownership.

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