Investors & Media

Ownership Profile

Ownership Profile

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Fidelity Management & Research Company 20,947,127 14.89 24,443 12/31/19
The Vanguard Group, Inc. 11,966,392 8.51 -248,083 12/31/19
Baillie Gifford & Co. 8,790,025 6.25 374,736 12/31/19
Bellevue Asset Management AG 8,431,820 5.99 109,906 12/31/19
ClearBridge Investments, LLC 7,947,576 5.65 -1,343,348 12/31/19
BlackRock Institutional Trust Company, N.A. 6,955,154 4.94 -8,776 12/31/19
Wellington Management Company, LLP 6,737,856 4.79 -1,007,483 12/31/19
Biogen Inc 5,750,577 4.09 -5,750,576 12/31/19
State Street Global Advisors (US) 3,847,385 2.74 196,602 12/31/19
Invesco Advisers, Inc. 2,331,852 1.66 -5,648 12/31/19

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Fidelity Growth Company Fund 8,514,444 6.12 228,918 2/29/20
BB Biotech Fd 7,994,955 5.74 -- 12/31/19
Vanguard Total Stock Market Index Fund 3,653,649 2.62 71,830 2/29/20
Vanguard Small-Cap Index Fund 3,240,446 2.33 -1,504 2/29/20
Hartford MidCap Fund 2,323,791 1.67 -141,796 2/29/20
ClearBridge Aggressive Growth Fund 2,306,791 1.66 -- 12/31/19
Fidelity Series Growth Company Fund 2,085,834 1.50 -55,100 2/29/20
Ivy Science and Technology Fund 2,045,947 1.47 -872,379 12/31/19
Vanguard Small-Cap Growth Index Fund 1,879,293 1.35 -20,864 2/29/20
Vanguard Extended Market Index Fund 1,818,302 1.31 -8,274 2/29/20

* Insider values reflect direct beneficial ownership.

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