Investor FAQ

If you are interested in Ionis Pharmaceuticals' investment details, you can find the answers to some frequently asked questions below.

  1. Where are you located?
  2. Can you provide a brief description of your Company?
  3. When was the Company founded and when did it go public?
  4. What is Ionis stock symbol and on what exchange is it traded?
  5. How many shares are outstanding?
  6. How can I purchase shares?
  7. How can I get a copy of your annual report?
  8. I have lost my stock certificates. How can I replace them?

Where are you located?
Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010
(Carlsbad is approximately 35 miles north of downtown San Diego.)
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Can you provide a brief description of your Company?
As the leader in RNA-targeted drug discovery and development, Ionis has created an efficient, broadly applicable, proprietary antisense technology platform with the potential to treat diseases where no other therapeutic approaches have proven effective. Our drug discovery platform has served as a springboard for actionable promise and realized hope for patients with unmet needs – such as children and adults with spinal muscular atrophy (SMA). We created SPINRAZA®(nusinersen)* and are proud to have brought new hope to the SMA community by developing the first and only approved treatment for this disease. 

Our sights are set on all the patients we have yet to reach with a pipeline of more than 40 drugs with the potential to treat patients with cardiovascular disease, rare diseases, neurological diseases, infectious diseases and cancer. We created TEGSEDI™ (inotersen) the world's first RNA-targeted therapeutic approved for the treatment of polyneuropathy of hereditary transthyretin (TTR) amyloidosis (ATTR) in adult patients that our affiliate Akcea Therapeutics is commercializing. Together with Akcea, we are also bringing new medicines to patients with cardiometabolic lipid disorders.

*Spinraza is marketed by Biogen.
 
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When was the Company founded and when did it go public?
Ionis Pharmaceuticals, Inc. was founded in 1989. Ionis conducted its initial public offering two years later in 1991.
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What is Ionis stock symbol and on what exchange is it traded?
Ionis is traded on the NASDAQ stock exchange under the symbol IONS. Please note that prior to December 22, 2015 our symbol was ISIS and prior to February 21, 2002 our symbol was ISIP.
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How many shares are outstanding?
The number of shares of voting common stock outstanding as of October 31, 2018 was 137,571,510.
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How can I purchase shares?
To purchase Ionis stock you may use the broker of your choice. Ionis does not offer a direct stock purchase plan.
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How can I get a copy of your annual report?
To view a PDF file of the annual reports from 2015-2017  click here. If you would like to receive a hard copy of any of Ionis' annual reports, please click here. Please note that if you are requesting that we send the annual report to an address outside of the U.S. (including Canada and Mexico) you must include your telephone number. The US Postal Service requires a phone number for shipments out of the U.S.
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I have lost my stock certificates. How can I replace them?
Contact our Transfer Agent, American Stock Transfer & Trust Company: American Stock Transfer & Trust Company (AST)
59 Maiden Lane
Plaza Level
New York, NY 10038
ATTN: Shareholder Services
Tel 1-800-937-5449
Tel 1-718-921-8206
http://www.amstock.com/main/ To begin the process, click here:
https://secure.amstock.com/shareholder/sh_login.asp
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©1999 - 2017 Ionis Pharmaceuticals™ is a trademark of Ionis Pharmaceuticals, Inc. Akcea Therapeutics™ is a trademark of Ionis Pharmaceuticals, Inc.